THC increases brain activity

Following administration of THC or placebo, researchers evaluated the brain activity during exposure to stimuli with negative or positive contents fearful faces and happy faces. The hypothesis is that the administration of THC could reduce the negative bias of the subjects in emotional processing and a positive attitude towards change.

A trend towards negative stimuli has been associated with the diagnosis of certain mental illnesses such as depression.  As expected, its reported reduced activity in the brain after administration of THC when stimuli processed subjects with a negative emotional content. Conversely, researchers reported increased brain activity following administration of THC when stimuli processed by the subjects had a positive emotional content.

They concluded: “These results indicate that administration of THC reduces the negative bias in emotional processing this adds evidence in humans to support the hypothesis that the endocannabinoid system is involved in the modulation of emotional processing The results also suggest a possible role of the endocannabinoid system in the abnormal emotional processing, and may therefore be relevant for psychiatric disorders such as major depression”.

THC increases brain activity

Treating depression with cannabinoids

Although there are a variety of drugs available for depression. Treatment is not always effective and it is advisable to keep looking new options for alternative results in animal models studies, anecdotal reports from the experience of cannabis clients’ observations of clinical trials when cannabinoids have been used in serious diseases suggest that cannabinoid receptor agonists have potential anti-depressant effect.

This study a series of clinical cases are shown, with promising results which has been used as a therapeutic dronabinol dart either alone or in combination with other antidepressants,

Subjectively, patients in numerous surveys and interviews, they have reported an anti-depressant effect of marijuana. Patients who suffer from chronic diseases claim that cannabis not only alleviates the physical symptoms, such as pain, nausea and lack of appetite, but also improves wellbeing and reduces generalized anxiety and depression.

Objectively it observed along several clinical studies, which were monitored subjective parameters. Cannabinoids not only they improved physical symptoms, but also led to improved welfare and antidepressant effects. For more queries visit

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